A proof-of-concept study of direct magnetic resonance imaging-based proton dose calculation for brain tumors via neural networks with Monte Carlo-comparable accuracy
This study demonstrated the feasibility of MC-quality proton dose calculations directly from MR images for brain tumor patients, achieving comparable accuracy with faster computation and simplified implementation.
Jul 5, 2025
Uncertainty-aware MR-based CT synthesis for robust proton therapy planning of brain tumour
The enhanced framework incorporates 3D uncertainty prediction and generates high-quality sCTs from MR images. The framework also facilitates conditioned robust optimisation, bolstering proton plan robustness against network prediction errors. The innovative feature of uncertainty visualisation and robust analyses contribute to evaluating sCT clinical utility for individual patients.
Feb 1, 2024