Contour-informed inter-patient deformable registration for more reliable voxel-based analysis of Head-and-Neck cancer patients
The integration of contour-informed regularization in CPT-DIR improved DIR accuracy, particularly in anatomically and dosimetrically relevant regions.
Jan 1, 2026
A Unified Generation-Registration Framework for Improved MR-based CT Synthesis in Proton Therapy
This study conclusively demonstrates that a holistic MR-based CT synthesis approach, integrating both image-to-image translation and deformable registration, significantly improves the precision and quality of sCT generation, particularly for the challenging body area with varied anatomic changes between corresponding MR and CT.
Aug 13, 2024
Uncertainty-aware MR-based CT synthesis for robust proton therapy planning of brain tumour
The enhanced framework incorporates 3D uncertainty prediction and generates high-quality sCTs from MR images. The framework also facilitates conditioned robust optimisation, bolstering proton plan robustness against network prediction errors. The innovative feature of uncertainty visualisation and robust analyses contribute to evaluating sCT clinical utility for individual patients.
Feb 1, 2024